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PhD Student (gn*) Biology, Molecular/Experimental Medicine, Biochemistry or related

PhD Student (gn*) Biology, Molecular/Experimental Medicine, Biochemistry or related

Universitätsklinikum Münster
locationKreisfreie Stadt Münster, 48 Münster, Deutschland
VeröffentlichtVeröffentlicht: 18.9.2025
Vollzeit
Mehrjährige Berufserfahrung
  • This project aims to uncover how microbiota-derived metabolites influence the endothelial barrier function and neutrophil transmigration, with an emphasis on their implications in aortic disease development and progression. A key component of the project will also explore general metabolite-mediated signaling in the aortic endothelium, aiming to identify novel molecular pathways involved in vascular inflammation and remodeling.
  • Analysis of human aortic tissue specimens
  • Execution of in vitro experiments using primary human aortic endothelial cells
  • Investigation of molecular mechanisms regulating endothelial barrier function and immune cell transmigration
  • Collaborative work with core facilities for genomics and proteomics to generate and analyze large-scale datasets
  • Identification and characterization of novel microbiota-metabolite-driven signaling pathways relevant to aortic endothelial function
  • Part of Research Innovation

Berufserfahrung

  • Mehrjährige Berufserfahrung